February Meetings: Thursday, February 16th - Engineers’ Week Dinner Celebration. Sponsored by the MESC (Metropolitan Engineering Societies Council). AIChE, Metro NY is a MESC Member. Topic: The Second Avenue Subway Project. Details.

Tuesday, February 21st - AIChE Metro’s Dinner Meeting at the Pfizer Building. Venue.

Please reserve early as these events sell out. Reserve Now. Students.

Advances in Biomedical Engineering: A Case Study

A CRISPR/Cas9 Application for Drug Delivery using Pentablock Copolymers

Speaker: Pratish Adhikari, Iowa State University

Abstract: CRISPR/Cas9 is a genome editing tool that is creating a buzz in the biomedical engineering world. It is faster, cheaper and more accurate than previous techniques of editing DNA, and has a wide range of potential applications.

Parkinson's and Alzheimer’s (Diseases) are the most common neurodegenerative disorders in the United States. Currently, these neurodegenerative disease can’t be cured, and medications are only used to treat symptoms.

In this study, an amphiphilic pentablock copolymer was shown to be effective for delivering a CRISPR/Cas9 gene-editing technique to treat genetic diseases. CRISPR/Cas9 was used to efficiently target a GMC-SF gene to decrease the gene’s effects on astrocyte that causes astroctytosis, which is a hallmark of various neurological injuries and inflammatory processes.

Bio: Our February speaker is Pratish Adhikari, a recent graduate from Iowa State University (ISU), with degrees in Chemical Engineering and Genetics. Pratish was born in the small south Asian country of Nepal.

During his undergraduate years, he was deeply involved in the neuroscience research lab of Dr. Surya Mallapragada. Pratish was an International Student Ambassador at ISU, where he assisted international students adjust to their life in United States. He was also member of the neuroscience research committee, the Society of Biological Engineers, and the American Institute of Chemical Engineers.

Among the projects that he was involved in included peripheral nerve injury, where his lab would manufacture polylactic acid polymer conduit, and bioengineer mesenchymal stem cells to astrocyte type cells. He assisted in in vivo studies (using a rat model) for determining optimal sciatic nerve recovery. He was also involved in a CRISPR/Cas9 drug delivery strategy for Parkinson's and Alzheimer's diseases.

Pratish has won first place for AICHE Student Poster Competition at the 2016 Mid-America Student Regional Conference, and third place for AICHE Student Poster competition at 2016 National Student Conference.

Costs: for Networking, Buffet, and Program. Reserve Now.

* Members of AIChE, Metro NY Section: $25

* Non- Members and Guests: $40

* PDH credits for New York State PEs (when offered): an addit. $10

* Undergraduates - Free for undergrads. You must
register. Seating is limited, so please reserve early.

* Graduate Students - $10. Please
reserve here. Also, please register.

Registration: ALL attendees MUST pre-register before the meeting... by Friday, Feb. 17th, 5 pm.

Program Details: The event begins at 5:30 pm with a Networking Event that includes a buffet supper (arriving at 6:00 pm) and with the presentation from 6:30 pm to 7:30 pm.  Attire: Professional casual attire is suggested. Please note the meeting room should be available about 5 pm - so early attendance is encouraged.

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If you are not a Member of this Section, you can apply the $15 additional amount paid as a Guest to a full Membership for 2017. Please notify Treasurer Andrew Sung that you wish to be a Member. Register Now.
Save the Dates: 2017 Meeting Dates
Tuesday, Feb. 21st
Monday, Mar. 20th
Monday, Apr. 17th
Monday, May 15th
Monday, Jun. 19th

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